Epidermolytic Hyperkeratosis – A rare case report.

A 20 year old boy presented to the dermatology department for treatment of a congenital icthyosis with a history of generalized erythroderma and trauma related blistering since birth. At the time of presentation he was noted to have red hyperkeratotic plaques all over the body. Lesions were corrugated over the joint flexures, elbows, knees, and dorsal of hands. In the subsequent months after birth erythema and blistering improved but patient developed hyperkeratotic scaling that was especially prominent over the joint flexures neck, hands and feet. Treatment options include urea or alpha-hydroxy acid containing creams as well as topical and systemic retinoids.

Acne: Etiopathogenesis and its management.

Acne vulgaris is one of the commonest skin disorders, which dermatologists have to treat, mainly affect adolescents, though it may present at any age. Acne is chronic inflammatory disease of pilosebaceous units. Clinically it can present as seborrhea, comedones, erythematous papules, pustules and nodules. In recent years, due to better understanding of the etiopathogenesis of acne, new therapeutic modalities are designed. The purpose of this article is to review the etiopathogenesis and treatment options available with us in the present scenario.

Parotid abscess in a seven year old child – A rare case report with review of literature.

A thirteen years old male patient of insulin dependent diabtes mellitus from Medicine Department was referred to our Dermatology Department with multiple eruptive xanthomas over the buttocks, knees and hands. Patient was blind since birth and diagnosis of “retinitis pigmentosa" was made by Ophthalmology Department. He was investigated and found raised levels of blood sugar, triglycerides, VLDL, TSH, SGOT/PT and kidney functions tests. He was diagnosed as a case of eruptive xanthomas with retinitis pigmentosa in secondary hyperlipidemia. We have reported this case because of the rare associations.

Study of the causes of vaginal discharge among sexually active females in age group of 20-45 years: A hospital based study in B.P.S. Government Medical College for Women, Khanpur Kalan, District Sonipat, Haryana, India.

Background: Vaginal discharge is a common symptom of genital infection in woman. Identifying its source can be challenging as large number of pathogens causes vaginal and cervical infection and several other infections may coexist. Aim: To find out the possible causes of vaginal infection in sexually active woman. Material and methods: One hundred sexually active females in the age group of 20-45 years with complaints of vaginal discharge were selected for the study. A detailed clinical history and a thorough clinical examination were carried out. After making the clinical diagnosis appropriate test for diagnosing candidiasis, trichomoniasis, gonorrhea and bacterial vaginosis were done. Results: The present study showed 34% incidence of bacterial Vaginosis,30% vulvo -veginal candidiasis, 14% trichomoniasis, 2% gonorrhea, 2% normal physiological discharge and 18% non specific urogenital infections. Conclusion: Every patient, who complains of vaginal discharge, should be thoroughly interrogated, examined and investigated properly.

Epidermal nevus syndrome associated with ocular symblepharon and gum hypertrophy – A rare variant.

Epidermal nevi are congenital hamartomas of embryonal ectodermal origin classified on the basis of their main component. The component may be sebaceous, apocrine, eccrine, follicular or keratinocytic. An estimated 1/3 of individuals with epidermal nevi have involvement of other organ systems; hence this condition is considered to be epidermal nevus syndrome. Solomon defined epidermal nevus syndrome as a sporadic neuro-cutaneous linkage of congenital ectodermal defects in the skin, brain, eyes and skeleton, now also referred to as Solomon syndrome. The syndromes are uncommon. Mortality and morbidity are associated with systemic anomalies.

Cutaneous manifestations of diabetes mellitus in controlled and uncontrolled state.

Background: Diabetes Mellitus can be complicated by a variety of cutaneous manifestations. Good metabolic control may prevent some of these manifestations and may support cure. Almost all diabetic patients eventually develop skin complications from long term effects of Diabetes Mellitus on the microcirculation and skin collagen. Cutaneous infections are more common in type 2 diabetes. Patients, who had diabetes for many years, tend to develop the most devastating skin problems. Aim: To evaluate the pattern of cutaneous manifestations in Diabetes Mellitus in controlled and uncontrolled State. Material and methods: Two hundred patients with the diagnosis of diabetes mellitus type-II (100 controlled and 100 uncontrolled) attending the outpatient departments of dermatology and medicine of B.P.S. Govt. Medical College, Khanpur Kalan, Dist. Sonepat were studied Results: Among the cutaneous disorders commonly associated with diabetes, infections (49%) were the most prevalent. Conclusion: One should be vigilant enough for the cutaneous manifestations as they are the window to the systemic illness.